SSRI Antidepressant Withdrawal Syndrome in Newborns
نویسنده
چکیده
Editor’s Note: Adverse drug reactions experienced by UWMC or HMC patients and reported to the pharmacy are reviewed quarterly by the Pharmacy & Therapeutics Committee. Following the Committee’s review, a summary is published in this newsletter (see page 9) along with a companion article regarding some aspect of adverse drug reactions. It is hoped that these articles will be useful tools to remind prescribers of the fundamental principle of pharmacology that states, “No drug has only one action.” By reminding prescribers to be alert to the appearance of undesired and unintended actions of drugs, therapeutic outcomes may be improved and adverse events minimized. If you have a patient you feel is experiencing an Adverse Drug Reaction, report it by calling the A.D.R. Phone Line, HMC: 731-3802; UWMC: 598-6837; SCCA: 288-6336.
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Selective Serotonin Reuptake Inhibitor Antidepressant Treatment Discontinuation Syndrome: A Review of the Clinical Evidence and the Possible Mechanisms Involved
Besides demonstrated efficacy, selective serotonin reuptake inhibitors (SSRIs) hold other advantages over earlier antidepressants such as greater tolerability and a wider range of clinical applications. However, there is a growing body of clinical evidence which suggests that SSRIs could, in some cases, be associated with a withdrawal reaction upon cessation of regular use. In addition to senso...
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Background: Selective serotonin reuptake inhibitors (SSRI) are widely used in medical practice. They have been associated with a broad range of symptoms, whose clinical meaning has not been fully appreciated. Methods: The PRISMA guidelines were followed to conduct a systematic review of the literature. Titles, abstracts, and topics were searched using the following terms: 'withdrawal symptoms' ...
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Several selective serotonin reuptake inhibitors (SSRI), especially paroxetine, have been reported to produce a number of post-treatment emergent adverse events following abrupt withdrawal (Coupland et al 1996; Haddad 1997). More recently a SSRI-induced neonatal withdrawal syndrome has been described (Sanz et al 2005) in infants born of mothers treated with SSRI during pregnancy. In both of thes...
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